Identify
Explore
Discover
Discuss
Summarise
Describe
Last, format your objectives into a numbered list. This is because when you write your thesis or dissertation, you will at times need to make reference to a specific research objective; structuring your research objectives in a numbered list will provide a clear way of doing this.
To bring all this together, let’s compare the first research objective in the previous example with the above guidance:
Research Objective:
1. Develop finite element models using explicit dynamics to mimic mallet blows during cup/shell insertion, initially using simplified experimentally validated foam models to represent the acetabulum.
Checking Against Recommended Approach:
Q: Is it specific? A: Yes, it is clear what the student intends to do (produce a finite element model), why they intend to do it (mimic cup/shell blows) and their parameters have been well-defined ( using simplified experimentally validated foam models to represent the acetabulum ).
Q: Is it measurable? A: Yes, it is clear that the research objective will be achieved once the finite element model is complete.
Q: Is it achievable? A: Yes, provided the student has access to a computer lab, modelling software and laboratory data.
Q: Is it relevant? A: Yes, mimicking impacts to a cup/shell is fundamental to the overall aim of understanding how they deform when impacted upon.
Q: Is it timebound? A: Yes, it is possible to create a limited-scope finite element model in a relatively short time, especially if you already have experience in modelling.
Q: Does it start with a verb? A: Yes, it starts with ‘develop’, which makes the intent of the objective immediately clear.
Q: Is it a numbered list? A: Yes, it is the first research objective in a list of eight.
1. making your research aim too broad.
Having a research aim too broad becomes very difficult to achieve. Normally, this occurs when a student develops their research aim before they have a good understanding of what they want to research. Remember that at the end of your project and during your viva defence , you will have to prove that you have achieved your research aims; if they are too broad, this will be an almost impossible task. In the early stages of your research project, your priority should be to narrow your study to a specific area. A good way to do this is to take the time to study existing literature, question their current approaches, findings and limitations, and consider whether there are any recurring gaps that could be investigated .
Note: Achieving a set of aims does not necessarily mean proving or disproving a theory or hypothesis, even if your research aim was to, but having done enough work to provide a useful and original insight into the principles that underlie your research aim.
Be realistic about what you can achieve in the time you have available. It is natural to want to set ambitious research objectives that require sophisticated data collection and analysis, but only completing this with six months before the end of your PhD registration period is not a worthwhile trade-off.
Each research objective should have its own purpose and distinct measurable outcome. To this effect, a common mistake is to form research objectives which have large amounts of overlap. This makes it difficult to determine when an objective is truly complete, and also presents challenges in estimating the duration of objectives when creating your project timeline. It also makes it difficult to structure your thesis into unique chapters, making it more challenging for you to write and for your audience to read.
Fortunately, this oversight can be easily avoided by using SMART objectives.
Hopefully, you now have a good idea of how to create an effective set of aims and objectives for your research project, whether it be a thesis, dissertation or research paper. While it may be tempting to dive directly into your research, spending time on getting your aims and objectives right will give your research clear direction. This won’t only reduce the likelihood of problems arising later down the line, but will also lead to a more thorough and coherent research project.
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The “Golden Thread” Explained Simply (+ Examples)
By: David Phair (PhD) and Alexandra Shaeffer (PhD) | June 2022
The research aims , objectives and research questions (collectively called the “golden thread”) are arguably the most important thing you need to get right when you’re crafting a research proposal , dissertation or thesis . We receive questions almost every day about this “holy trinity” of research and there’s certainly a lot of confusion out there, so we’ve crafted this post to help you navigate your way through the fog.
The golden thread simply refers to the collective research aims , research objectives , and research questions for any given project (i.e., a dissertation, thesis, or research paper ). These three elements are bundled together because it’s extremely important that they align with each other, and that the entire research project aligns with them.
Importantly, the golden thread needs to weave its way through the entirety of any research project , from start to end. In other words, it needs to be very clearly defined right at the beginning of the project (the topic ideation and proposal stage) and it needs to inform almost every decision throughout the rest of the project. For example, your research design and methodology will be heavily influenced by the golden thread (we’ll explain this in more detail later), as well as your literature review.
The research aims, objectives and research questions (the golden thread) define the focus and scope ( the delimitations ) of your research project. In other words, they help ringfence your dissertation or thesis to a relatively narrow domain, so that you can “go deep” and really dig into a specific problem or opportunity. They also help keep you on track , as they act as a litmus test for relevance. In other words, if you’re ever unsure whether to include something in your document, simply ask yourself the question, “does this contribute toward my research aims, objectives or questions?”. If it doesn’t, chances are you can drop it.
Alright, enough of the fluffy, conceptual stuff. Let’s get down to business and look at what exactly the research aims, objectives and questions are and outline a few examples to bring these concepts to life.
Simply put, the research aim(s) is a statement that reflects the broad overarching goal (s) of the research project. Research aims are fairly high-level (low resolution) as they outline the general direction of the research and what it’s trying to achieve .
True to the name, research aims usually start with the wording “this research aims to…”, “this research seeks to…”, and so on. For example:
“This research aims to explore employee experiences of digital transformation in retail HR.” “This study sets out to assess the interaction between student support and self-care on well-being in engineering graduate students”
As you can see, these research aims provide a high-level description of what the study is about and what it seeks to achieve. They’re not hyper-specific or action-oriented, but they’re clear about what the study’s focus is and what is being investigated.
The research objectives take the research aims and make them more practical and actionable . In other words, the research objectives showcase the steps that the researcher will take to achieve the research aims.
The research objectives need to be far more specific (higher resolution) and actionable than the research aims. In fact, it’s always a good idea to craft your research objectives using the “SMART” criteria. In other words, they should be specific, measurable, achievable, relevant and time-bound”.
Let’s look at two examples of research objectives. We’ll stick with the topic and research aims we mentioned previously.
For the digital transformation topic:
To observe the retail HR employees throughout the digital transformation. To assess employee perceptions of digital transformation in retail HR. To identify the barriers and facilitators of digital transformation in retail HR.
And for the student wellness topic:
To determine whether student self-care predicts the well-being score of engineering graduate students. To determine whether student support predicts the well-being score of engineering students. To assess the interaction between student self-care and student support when predicting well-being in engineering graduate students.
As you can see, these research objectives clearly align with the previously mentioned research aims and effectively translate the low-resolution aims into (comparatively) higher-resolution objectives and action points . They give the research project a clear focus and present something that resembles a research-based “to-do” list.
Finally, we arrive at the all-important research questions. The research questions are, as the name suggests, the key questions that your study will seek to answer . Simply put, they are the core purpose of your dissertation, thesis, or research project. You’ll present them at the beginning of your document (either in the introduction chapter or literature review chapter) and you’ll answer them at the end of your document (typically in the discussion and conclusion chapters).
The research questions will be the driving force throughout the research process. For example, in the literature review chapter, you’ll assess the relevance of any given resource based on whether it helps you move towards answering your research questions. Similarly, your methodology and research design will be heavily influenced by the nature of your research questions. For instance, research questions that are exploratory in nature will usually make use of a qualitative approach, whereas questions that relate to measurement or relationship testing will make use of a quantitative approach.
Let’s look at some examples of research questions to make this more tangible.
Again, we’ll stick with the research aims and research objectives we mentioned previously.
For the digital transformation topic (which would be qualitative in nature):
How do employees perceive digital transformation in retail HR? What are the barriers and facilitators of digital transformation in retail HR?
And for the student wellness topic (which would be quantitative in nature):
Does student self-care predict the well-being scores of engineering graduate students? Does student support predict the well-being scores of engineering students? Do student self-care and student support interact when predicting well-being in engineering graduate students?
You’ll probably notice that there’s quite a formulaic approach to this. In other words, the research questions are basically the research objectives “converted” into question format. While that is true most of the time, it’s not always the case. For example, the first research objective for the digital transformation topic was more or less a step on the path toward the other objectives, and as such, it didn’t warrant its own research question.
So, don’t rush your research questions and sloppily reword your objectives as questions. Carefully think about what exactly you’re trying to achieve (i.e. your research aim) and the objectives you’ve set out, then craft a set of well-aligned research questions . Also, keep in mind that this can be a somewhat iterative process , where you go back and tweak research objectives and aims to ensure tight alignment throughout the golden thread.
Alignment is the keyword here and we have to stress its importance . Simply put, you need to make sure that there is a very tight alignment between all three pieces of the golden thread. If your research aims and research questions don’t align, for example, your project will be pulling in different directions and will lack focus . This is a common problem students face and can cause many headaches (and tears), so be warned.
Take the time to carefully craft your research aims, objectives and research questions before you run off down the research path. Ideally, get your research supervisor/advisor to review and comment on your golden thread before you invest significant time into your project, and certainly before you start collecting data .
In this post, we unpacked the golden thread of research, consisting of the research aims , research objectives and research questions . You can jump back to any section using the links below.
As always, feel free to leave a comment below – we always love to hear from you. Also, if you’re interested in 1-on-1 support, take a look at our private coaching service here.
This post was based on one of our popular Research Bootcamps . If you're working on a research project, you'll definitely want to check this out ...
Thank you very much for your great effort put. As an Undergraduate taking Demographic Research & Methodology, I’ve been trying so hard to understand clearly what is a Research Question, Research Aim and the Objectives in a research and the relationship between them etc. But as for now I’m thankful that you’ve solved my problem.
Well appreciated. This has helped me greatly in doing my dissertation.
An so delighted with this wonderful information thank you a lot.
so impressive i have benefited a lot looking forward to learn more on research.
I am very happy to have carefully gone through this well researched article.
Infact,I used to be phobia about anything research, because of my poor understanding of the concepts.
Now,I get to know that my research question is the same as my research objective(s) rephrased in question format.
I please I would need a follow up on the subject,as I intends to join the team of researchers. Thanks once again.
Thanks so much. This was really helpful.
I know you pepole have tried to break things into more understandable and easy format. And God bless you. Keep it up
i found this document so useful towards my study in research methods. thanks so much.
This is my 2nd read topic in your course and I should commend the simplified explanations of each part. I’m beginning to understand and absorb the use of each part of a dissertation/thesis. I’ll keep on reading your free course and might be able to avail the training course! Kudos!
Thank you! Better put that my lecture and helped to easily understand the basics which I feel often get brushed over when beginning dissertation work.
This is quite helpful. I like how the Golden thread has been explained and the needed alignment.
This is quite helpful. I really appreciate!
The article made it simple for researcher students to differentiate between three concepts.
Very innovative and educational in approach to conducting research.
I am very impressed with all these terminology, as I am a fresh student for post graduate, I am highly guided and I promised to continue making consultation when the need arise. Thanks a lot.
A very helpful piece. thanks, I really appreciate it .
Very well explained, and it might be helpful to many people like me.
Wish i had found this (and other) resource(s) at the beginning of my PhD journey… not in my writing up year… 😩 Anyways… just a quick question as i’m having some issues ordering my “golden thread”…. does it matter in what order you mention them? i.e., is it always first aims, then objectives, and finally the questions? or can you first mention the research questions and then the aims and objectives?
Thank you for a very simple explanation that builds upon the concepts in a very logical manner. Just prior to this, I read the research hypothesis article, which was equally very good. This met my primary objective.
My secondary objective was to understand the difference between research questions and research hypothesis, and in which context to use which one. However, I am still not clear on this. Can you kindly please guide?
In research, a research question is a clear and specific inquiry that the researcher wants to answer, while a research hypothesis is a tentative statement or prediction about the relationship between variables or the expected outcome of the study. Research questions are broader and guide the overall study, while hypotheses are specific and testable statements used in quantitative research. Research questions identify the problem, while hypotheses provide a focus for testing in the study.
Exactly what I need in this research journey, I look forward to more of your coaching videos.
This helped a lot. Thanks so much for the effort put into explaining it.
What data source in writing dissertation/Thesis requires?
What is data source covers when writing dessertation/thesis
This is quite useful thanks
I’m excited and thankful. I got so much value which will help me progress in my thesis.
where are the locations of the reserch statement, research objective and research question in a reserach paper? Can you write an ouline that defines their places in the researh paper?
Very helpful and important tips on Aims, Objectives and Questions.
Thank you so much for making research aim, research objectives and research question so clear. This will be helpful to me as i continue with my thesis.
Thanks much for this content. I learned a lot. And I am inspired to learn more. I am still struggling with my preparation for dissertation outline/proposal. But I consistently follow contents and tutorials and the new FB of GRAD Coach. Hope to really become confident in writing my dissertation and successfully defend it.
As a researcher and lecturer, I find splitting research goals into research aims, objectives, and questions is unnecessarily bureaucratic and confusing for students. For most biomedical research projects, including ‘real research’, 1-3 research questions will suffice (numbers may differ by discipline).
Awesome! Very important resources and presented in an informative way to easily understand the golden thread. Indeed, thank you so much.
Well explained
The blog article on research aims, objectives, and questions by Grad Coach is a clear and insightful guide that aligns with my experiences in academic research. The article effectively breaks down the often complex concepts of research aims and objectives, providing a straightforward and accessible explanation. Drawing from my own research endeavors, I appreciate the practical tips offered, such as the need for specificity and clarity when formulating research questions. The article serves as a valuable resource for students and researchers, offering a concise roadmap for crafting well-defined research goals and objectives. Whether you’re a novice or an experienced researcher, this article provides practical insights that contribute to the foundational aspects of a successful research endeavor.
A great thanks for you. it is really amazing explanation. I grasp a lot and one step up to research knowledge.
I really found these tips helpful. Thank you very much Grad Coach.
I found this article helpful. Thanks for sharing this.
thank you so much, the explanation and examples are really helpful
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In this part, we give you detailed information about writing an effective Research Plan. We start with the importance and parameters of significance and innovation.
We then discuss how to focus the Research Plan, relying on the iterative process described in the Iterative Approach to Application Planning Checklist shown at Draft Specific Aims and give you advice for filling out the forms.
You'll also learn the importance of having a well-organized, visually appealing application that avoids common missteps and the importance of preparing your just-in-time information early.
While this document is geared toward the basic research project grant, the R01, much of it is useful for other grant types.
Research plan overview and your approach, craft a title, explain your aims, research strategy instructions, advice for a successful research strategy, graphics and video, significance, innovation, and approach, tracking for your budget, preliminary studies or progress report, referencing publications, review and finalize your research plan, abstract and narrative.
Your application's Research Plan has two sections:
In your Specific Aims, you note the significance and innovation of your research; then list your two to three concrete objectives, your aims.
Your Research Strategy is the nuts and bolts of your application, where you describe your research rationale and the experiments you will conduct to accomplish each aim. Though how you organize it is largely up to you, NIH expects you to follow these guidelines.
To write the Research Plan, you don't need the application forms. Write the text in your word processor, turn it into a PDF file, and upload it into the application form when it's final.
Because NIH may return your application if it doesn't meet all requirements, be sure to follow the rules for font, page limits, and more. Read the instructions at NIH’s Format Attachments .
For an R01, the Research Strategy can be up to 12 pages, plus one page for Specific Aims. Don't pad other sections with information that belongs in the Research Plan. NIH is on the lookout and may return your application to you if you try to evade page limits.
As you read this page, look at our Sample Applications and More to see some of the different strategies successful PIs use to create an outstanding Research Plan.
Writing in a logical sequence will save you time.
Information you put in the Research Plan affects just about every other application part. You'll need to keep everything in sync as your plans evolve during the writing phase.
It's best to consider your writing as an iterative process. As you develop and finalize your experiments, you will go back and check other parts of the application to make sure everything is in sync: the "who, what, when, where, and how (much money)" as well as look again at the scope of your plans.
In that vein, writing in a logical sequence is a good approach that will save you time. We suggest proceeding in the following order:
Even the smaller sections of your application need to be well-organized and readable so reviewers can readily grasp the information. If writing is not your forte, get help.
To view writing strategies for successful applications, see our Sample Applications and More . There are many ways to create a great application, so explore your options.
Within the character limit, include the important information to distinguish your project within the research area, your project's goals, and the research problem.
Giving your project a title at the outset can help you stay focused and avoid a meandering Research Plan. So you may want to launch your writing by creating a well-defined title.
NIH gives you a 200 character limit, but don’t feel obliged to use all of that allotment. Instead, we advise you to keep the title as succinct as possible while including the important information to distinguish your project within the research area. Make your title reflect your project's goals, the problem your project addresses, and possibly your approach to studying it. Make your title specific: saying you are studying lymphocyte trafficking is not informative enough.
For examples of strong titles, see our Sample Applications and More .
After you write a preliminary title, check that
Later you may want to change your initial title. That's fine—at this point, it's just an aid to keep your plans focused.
Since all your reviewers read your Specific Aims, you want to excite them about your project.
If testing your hypothesis is the destination for your research, your Research Plan is the map that takes you there.
You'll start by writing the smaller part, the Specific Aims. Think of the one-page Specific Aims as a capsule of your Research Plan. Since all your reviewers read your Specific Aims, you want to excite them about your project.
For more on crafting your Specific Aims, see Draft Specific Aims .
Use at least half the page to provide the rationale and significance of your planned research. A good way to start is with a sentence that states your project's goals.
For the rest of the narrative, you will describe the significance of your research, and give your rationale for choosing the project. In some cases, you may want to explain why you did not take an alternative route.
Then, briefly describe your aims, and show how they build on your preliminary studies and your previous research. State your hypothesis.
If it is likely your application will be reviewed by a study section with broad expertise, summarize the status of research in your field and explain how your project fits in.
In the narrative part of the Specific Aims of many outstanding applications, people also used their aims to
Depending on your situation, decide which items are important for you. For example, a new investigator would likely want to highlight preliminary data and qualifications to do the work.
Many people use bold or italics to emphasize items they want to bring to the reviewers' attention, such as the hypothesis or rationale.
After the narrative, enter your aims as bold bullets, or stand-alone or run-on headers.
How focused should your aims be? Look at the example below.
Read the Specific Aims of the Application from Drs. Li and Samulski , "Enhance AAV Liver Transduction with Capsid Immune Evasion."
After finishing the draft Specific Aims, check that
For each element listed above, analyze your text and revise it until your Specific Aims hit all the key points you'd like to make.
After the list of aims, some people add a closing paragraph, emphasizing the significance of the work, their collaborators, or whatever else they want to focus reviewers' attention on.
Your Research Strategy is the bigger part of your application's Research Plan (the other part is the Specific Aims—discussed above.)
The Research Strategy is the nuts and bolts of your application, describing the rationale for your research and the experiments you will do to accomplish each aim. It is structured as follows:
Though how you organize your application is largely up to you, NIH does want you to follow these guidelines:
For an R01, the Research Strategy is limited to 12 pages for the three main sections and the preliminary studies only. Other items are not included in the page limit.
Find instructions for R01s in the SF 424 Application Guide—go to NIH's SF 424 (R&R) Application and Electronic Submission Information for the generic SF 424 Application Guide or find it in your notice of funding opportunity (NOFO).
For most applications, you need to address Rigor and Reproducibility by describing the experimental design and methods you propose and how they will achieve robust and unbiased results. The requirement applies to research grant, career development, fellowship, and training applications.
If you're responding to an institute-specific program announcement (PA) (not a parent program announcement) or a request for applications (RFA), check the NIH Guide notice, which has additional information you need. Should it differ from the NOFO, go with the NIH Guide .
Also note that your application must meet the initiative's objectives and special requirements. NIAID program staff will check your application, and if it is not responsive to the announcement, your application will be returned to you without a review.
When writing your Research Strategy, your goal is to present a well-organized, visually appealing, and readable description of your proposed project. That means your writing should be streamlined and organized so your reviewers can readily grasp the information. If writing is not your forte, get help.
There are many ways to create an outstanding Research Plan, so explore your options.
Your application's Research Plan is the map that shows your reviewers how you plan to test your hypothesis.
It not only lays out your experiments and expected outcomes, but must also convince your reviewers of your likely success by allaying any doubts that may cross their minds that you will be able to conduct the research.
Notice in the sample applications how the writing keeps reviewers' eyes on the ball by bringing them back to the main points the PIs want to make. Write yourself an insurance policy against human fallibility: if it's a key point, repeat it, then repeat it again.
So as you write, put the big picture squarely in your sights. When reviewers read your application, they'll look for the answers to three basic questions:
Savvy PIs create opportunities to drive their main points home. They don't stop at the Significance section to emphasize their project's importance, and they look beyond their biosketches to highlight their team's expertise.
Don't take a chance your reviewer will gloss over that one critical sentence buried somewhere in your Research Strategy or elsewhere. Write yourself an insurance policy against human fallibility: if it's a key point, repeat it, then repeat it again.
Add more emphasis by putting the text in bold, or bold italics (in the modern age, we skip underlining—it's for typewriters).
Here are more strategies from our successful PIs:
You can see many of these principles at work in the Approach section of the Application from Dr. William Faubion , "Inflammatory cascades disrupt Treg function through epigenetic mechanisms."
Our applicants not only wrote with their reviewers in mind they seemed to anticipate their questions. You may think: how can I anticipate all the questions people may have? Of course you can't, but there are some basic items (in addition to the "big three" listed above) that will surely be on your reviewers' minds:
Address these questions; then spend time thinking about more potential issues specific to you and your research—and address those too.
For applications, a picture can truly be worth a thousand words. Graphics can illustrate complex information in a small space and add visual interest to your application.
Look at our sample applications to see how the investigators included schematics, tables, illustrations, graphs, and other types of graphics to enhance their applications.
Consider adding a timetable or flowchart to illustrate your experimental plan, including decision trees with alternative experimental pathways to help your reviewers understand your plans.
If you plan to send one or more videos, you'll need to meet certain standards and include key information in your Research Strategy now.
To present some concepts or demonstrations, video may enhance your application beyond what graphics alone can achieve. However, you can't count on all reviewers being able to see or hear video, so you'll want to be strategic in how you incorporate it into your application.
Be reviewer-friendly. Help your cause by taking the following steps:
In addition to those considerations, create your videos to fit NIH’s technical requirements. Learn more in the SF 424 Form Instructions .
Next, as you write your Research Strategy, include key images from the video and a brief description.
Then, state in your cover letter that you plan to send video later. (Don't attach your files to the application.)
After you apply and get assignment information from the Commons, ask your assigned scientific review officer (SRO) how your business official should send the files. Your video files are due at least one month before the peer review meeting.
The primary audience for your application is your peer review group. Learn how to write for the reviewers who are experts in your field and those who are experts in other fields by reading Know Your Audience .
In the top-notch applications we reviewed, organization ruled but followed few rules. While you want to be organized, how you go about it is up to you.
Nevertheless, here are some principles to follow:
The Research Strategy's page limit—12 for R01s—is for the three main parts: Significance, Innovation, and Approach and your preliminary studies (or a progress report if you're renewing your grant). Other sections, for example, research animals or select agents, do not have a page limit.
Although you will emphasize your project's significance throughout the application, the Significance section should give the most details. Don't skimp—the farther removed your reviewers are from your field, the more information you'll need to provide on basic biology, importance of the area, research opportunities, and new findings.
When you describe your project's significance, put it in the context of 1) the state of your field, 2) your long-term research plans, and 3) your preliminary data.
In our Sample Applications , you can see that both investigators and reviewers made a case for the importance of the research to improving human health as well as to the scientific field.
Look at the Significance section of the Application from Dr. Mengxi Jiang , "Intersection of polyomavirus infection and host cellular responses," to see how these elements combine to make a strong case for significance.
After conveying the significance of the research in several parts of the application, check that
If you are either a new PI or entering a new area: be cautious about seeming too innovative. Not only is innovation just one of five review criteria, but there might be a paradigm shift in your area of science. A reviewer may take a challenge to the status quo as a challenge to his or her world view.
When you look at our sample applications, you see that both the new and experienced investigators are not generally shifting paradigms. They are using new approaches or models, working in new areas, or testing innovative ideas.
After finishing the draft innovation section, check that
In your Approach, you spell out a few sets of experiments to address each aim. As we noted above, it's a good idea to restate the key points you've made about your project's significance, its place in your field, and your long-term goals.
You're probably wondering how much detail to include.
If you look at our sample applications as a guide, you can see very different approaches. Though people generally used less detail than you'd see in a scientific paper, they do include some experimental detail.
Expect your assigned reviewers to scrutinize your approach: they will want to know what you plan to do and how you plan to do it.
NIH data show that of the peer review criteria, approach has the highest correlation with the overall impact score.
Look at the Application from Dr. Mengxi Jiang , "Intersection of polyomavirus infection and host cellular responses," to see how a new investigator handled the Approach section.
For an example of an experienced investigator's well-received Approach section, see the Application from Dr. William Faubion , "Inflammatory cascades disrupt Treg function through epigenetic mechanisms."
Especially if you are a new investigator, you need enough detail to convince reviewers that you understand what you are undertaking and can handle the method.
Be sure to lay out a plan for alternative experiments and approaches in case you get negative or surprising results. Show reviewers you have a plan for spending the four or five years you will be funded no matter where the experiments lead.
See the Application from Drs. Li and Samulski , "Enhance AAV Liver Transduction with Capsid Immune Evasion," for a strong Approach section covering potential. As an example, see section C.1.3.'s alternative approaches.
Here are some pointers for organizing your Approach:
Trim the fat—omit all information not needed to make your case. If you try to wow reviewers with your knowledge, they'll find flaws and penalize you heavily. Don't give them ammunition by including anything you don't need.
As you design your experiments, keep a running tab of the following essential data on a separate piece of paper:
Jotting this information down will help you Create a Budget and complete other sections later.
After finishing a draft Approach section, check that
If you are applying for a new application, include preliminary studies; for a renewal or a revision (a competing supplement to an existing grant), prepare a progress report instead.
Your preliminary studies show that you can handle the methods and interpret results. Here's where you build reviewer confidence that you are headed in the right direction by pursuing research that builds on your accomplishments.
Reviewers use your preliminary studies together with the biosketches to assess the investigator review criterion, which reflects the competence of the research team.
Give alternative interpretations to your data to show reviewers you've thought through problems in-depth and are prepared to meet future challenges. If you don't do this, the reviewers will!
Though you may include other people's publications, focus on your preliminary data or unpublished data from your lab and the labs of your team members as much as you can.
As we noted above, you can put your preliminary data anywhere in the Research Strategy that you feel is appropriate, but just make sure your reviewers will be able to distinguish it. Alternatively, you can create a separate section with its own header.
If you are applying for a renewal or a revision (a competing supplement to an existing grant), prepare a progress report instead of preliminary studies.
Create a header so your program officer can easily find it and include the following information:
Note: if you submit a renewal application before the due date of your progress report, you do not need to submit a separate progress report for your grant. However, you will need to submit it, if your renewal is not funded.
After finishing the draft, check that
References show your breadth of knowledge of the field. If you leave out an important work, reviewers may assume you're not aware of it.
Throughout your application, you will reference all relevant publications for the concepts underlying your research and your methods.
Read more about your Bibliography and References Cited at Add a Bibliography and Appendix .
Look over what you've written with a critical eye of a reviewer to identify potential questions or weak spots.
Enlist others to do that too—they can look at your application with a fresh eye. Include people who aren't familiar with your research to make sure you can get your point across to someone outside your field.
As you finalize the details of your Research Strategy, you will also need to return to your Specific Aims to see if you must revise. See Draft Specific Aims .
After you finish your Research Plan, you are ready to write your Abstract (called Project Summary/Abstract) and Project Narrative, which are attachments to the Other Project Information form.
These sections may be small, but they're important.
Be sure to omit confidential or proprietary information in these sections! When your application is funded, NIH enters your title and Abstract in the public RePORTER database.
Think brief and simple: to the extent that you can, write these sections in lay language, and include appropriate keywords, e.g., immunotherapy, genetic risk factors.
As NIH referral officers use these parts to direct your application to an institute for possible funding, your description can influence the choice they make.
Write a succinct summary of your project that both a scientist and a lay person can understand (to the extent that you can).
In your Project Narrative, you have only a few sentences to drive home your project's potential to improve public health.
Check out these effective Abstracts and Narratives from our R01 Sample Applications :
Have questions.
A program officer in your area of science can give you application advice, NIAID's perspective on your research, and confirmation that your proposed research fits within NIAID’s mission.
Find contacts and instructions at When to Contact an NIAID Program Officer .
This nci sbir plan webinar series focuses on: how to write a good specific aims page.
The specific aims page is a critical part of an SBIR/STTR application. The aims page should be treated as a standalone page from which a reviewer can gain a reasonable understanding of the critical components of the project without reading any other parts of the application.
The first half of the aims page should cover key background information, highlighting the product, its significance, and innovation. The second half of the aims page should state the specific aims and milestones to be completed. Applicants are only allowed one-page for their specific aims.
In this PLAN series, prior SBIR/STTR awardees with a variety of cancer technology products such as therapeutics, diagnostics, devices, and digital health explain how they tackled various issues related to writing a good specific aims page, including but not limited to adding quantitative milestones, writing aims page for fast track or phase 2 applications, and more. Please find advice videos from each panelist below.
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Published by Grace Graffin at January 27th, 2023 , Revised On October 9, 2023
Aims and objectives are among the essential aspects of a dissertation. If you write aims and objectives effectively, they can act as a foundation to give your research clarity and focus.
This article will provide you with all the necessary information regarding aims and objectives, their differences, writing tips , and the common mistakes you should avoid while writing them.
The aim is often a single sentence or a short paragraph that describes your dissertation’s main goal and intent. It tells what you hope to achieve at the end. You should write the aim so that it becomes identifiable when it is achieved with the completion of your dissertation .
The aim is written in a subsection of the introduction to clarify the overall purpose of the dissertation .
Example: It is often observed that employees in culturally diverse workplaces struggle to work effectively in a team. A probable cause of this issue is bullying at the workplace. This research investigates the impact of bullying on employee job satisfaction at culturally diverse workplaces and the resulting loss of employee productivity. This research will use surveys and case study analysis to analyze the impact of bullying on employees.
The objectives in a dissertation describe the ways through which you intend to achieve the research aim. They are specific statements that break down the aim into several smaller key sections of the overall research. Suitable objectives can help you stay focused and conduct research in the direction of your aim.
The number of objectives should be realistic; usually, between three to six, and each one should be possible to achieve. The following example shows the objectives for the previously-mentioned dissertation aim.
1. identification of the behaviors that are considered as bullying 2. exploring the factors that cause bullying at a culturally diverse workplace 3. analyzing the relationship between bullying and job satisfaction of employees 4. providing suitable recommendations on minimizing the bullying at the workplace
The objectives of a dissertation should be SMART.
Aims and objectives are often mixed, but there are clear differences between them.
Aims | Objectives |
---|---|
describes “what” you intend to achieve through your research | focus on “how” you will achieve the aim |
usually written in broad terms covering the entire dissertation | are specific statements describing steps through which the research aim will be achieved |
is written as a single sentence or a small paragraph | should be written as a numbered list. |
focuses on long-term outcomes | focus on short-term and immediate outcomes. |
Orders completed by our expert writers are
There is no particular way or standard to write the aims and objectives. Different researchers have different writing styles, and often it can be influenced by your research supervisor. However, you should follow certain basic principles while writing aims and objectives in a dissertation.
The aim statement should cover the following essential elements.
An appropriate aim clearly defines the research purpose without confusing the reader. If you struggle to explain your research and its importance in simpler terms, you should consider refining your research to clarify it further.
The objectives describe how you would achieve your research aim. You can do this through the following steps,
Instead of writing like a paragraph, the objectives should be written as a numbered list to give them more clarity.
It depends upon the topic of your research and mainly upon your supervisor’s requirements. Generally, a dissertation has a single broad statement as the research aim. However, it is acceptable to include a main aim along with two to three subsidiary aims.
Similarly, the number of objectives should be realistic and sufficient to measure the progress regarding the achievement of the research aim. Their number can generally vary from three to six depending upon the aim.
Writing a broad research aim is a common mistake, and it often becomes difficult to achieve. It may create a problem when you are asked to prove how you have achieved your aims during your viva defense . It would be best to narrow your study to a specific area in the early stages of the dissertation.
The objectives should be written such that they are measurable and distinct from each other. If they overlap, it makes it difficult to structure your dissertation properly in specific chapters.
Students often get over-ambitious while describing the research aim and face problems afterward in achieving those aims. You should avoid this mistake and be realistic about what you can achieve in the available time and resources.
Aims and objectives are the sections that require significant time and attention to avoid future hassles while conducting research and writing your dissertation.
How to set dissertation aims and objectives.
To set dissertation aims and objectives, define your research goals clearly. Aims state what you want to achieve, while objectives outline specific, measurable steps to reach those goals. Ensure they align with your research question and contribute to your study’s significance.
Here is how coursework & dissertation are similar: Both test knowledge & require research (coursework applies, dissertation expands).
Achieving a 95% on your dissertation? We reveal insider tips & discuss if it’s even possible. Aim for dissertation excellence!
What are the key factors influencing language development and what can do to accelerate the process of language acquisition? Here is all you need to know!
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The Specific Aims (for NIH) or Objectives (NSF) are the key to what you are proposing. You want them to be not only clearly understandable to your reviewer (right?), but also captivating and interesting. It seems like a straight-forward writing goal, but unfortunately, I’ve seen many people wander off into confusing, overly-detailed, or just plain boring aims.
So, what makes an Aim / Objective really WORK?
In this video, I take two separate, high scoring NIH proposals in different fields, and examine the primary Aims. I break them down for you into 3 major parts, and what you want to communicate in each of these parts (very concisely!).
Watch this if you want to ensure the Aims you write are connecting with your reviewers.
If you want more clarity on getting funded in our currently crazy environment, I’ve got a free online training that will teach you how to get your reviewers excited and ready to fund your project. Sign up here.
dear dr giddings and team–your live event isn’t accessible yet–and it’s 7 minutes after. unfortunately we can’t all sit at our computers and wait
I sincerely apologize. I thought I was broadcasting, but due to a newbie type mistake, I wasn’t. I restarted about 15 minutes in, I realize some people will not have had time to wait that long.
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Click here to download a .pdf copy of our Beginner’s Guide to Research !
Last updated : July 18, 2024
Consider keeping a printed copy to have when writing and revising your resume! If you have any additional questions, make an appointment or email us at [email protected] !
Most professors will require the use of academic (AKA peer-reviewed) sources for student writing. This is because these sources, written for academic audiences of specific fields, are helpful for developing your argument on many topics of interest in the academic realm, from history to biology. While popular sources like news articles also often discuss topics of interest within academic fields, peer-reviewed sources offer a depth of research and expertise that you cannot find in popular sources. Therefore, knowing how to (1) identify popular vs. academic sources, (2) differentiate between primary and secondary sources, and (3) find academic sources is a vital step in writing research. Below are definitions of the two ways scholars categorize types of sources based on when they were created (i.e. time and place) and how (i.e. methodology):
Finding appropriate academic sources from the hundreds of different journal publications can be daunting. Therefore, it is important to find databases –digital collections of articles–relevant to your topic to narrow your search. Albertson’s Library has access to several different databases, which can be located by clicking the “Articles and Databases” tab on the website’s homepage, and navigating to “Databases A-Z” to refine your search. Popular databases include: Academic Search Premier and Proquest Central (non-specific databases which include a wide variety of articles), JSTOR (humanities and social sciences, from literature to history), Web of Science (formal sciences and natural sciences such as biology and chemistry), and Google Scholar (a web search engine that searches scholarly literature and academic sources). If you are unable to access articles from other databases, make sure you’re signed in to Alberton’s Library through Boise State!
Databases include many different types of sources besides academic journals, however, including book reviews and other periodicals. Using the search bar , you can limit search results to those containing specific keywords or phrases like “writing center” or “transfer theory.” Utilizing keywords in your search–names of key concepts, authors, or ideas–rather than questions is the most effective way to find articles in databases. When searching for a specific work by title, placing the title in quotation marks will ensure your search includes only results in that specific word order. In the example below, search terms including the author (“Virginia Woolf”) and subject (“feminism”) are entered into the popular database EBSCOhost:
Many databases have a bar on the left of the screen where you can further refine your results. For example, if you are only interested in finding complete scholarly articles, or peer-reviewed ones, you can toggle these different options to further limit your search. These options are located under the “Refine Results” bar in EBSCOhost, divided into different sections, with a display of currently selected search filters and filter options to refine your search based on your specific needs, as seen in the figure below:
Search results can also be limited by subject : If you search “Romeo and Juliet” on Academic Search Premier to find literary analysis articles for your English class, you’ll find a lot of other sources that include this search term, such as ones about theater production or ballets based on Shakespeare’s play. However, if you’re writing a literary paper on the text of the play itself, you might limit your search results to “fiction” to see only articles that discuss the play within the field of literature. Alternatively, for a theater class discussing the play, you might limit your search results to “drama.”
Remember: Less is more.
A strong presentation is so much more than information pasted onto a series of slides with fancy backgrounds. Whether you’re pitching an idea, reporting market research, or sharing something else, a great presentation can give you a competitive advantage, and be a powerful tool when aiming to persuade, educate, or inspire others. Here are some unique elements that make a presentation stand out.
As an intern or early career professional, chances are that you’ll be tasked with making or giving a presentation in the near future. Whether you’re pitching an idea, reporting market research, or sharing something else, a great presentation can give you a competitive advantage, and be a powerful tool when aiming to persuade, educate, or inspire others.
Project 2025 is an effort by the heritage foundation, not donald trump | fact check.
A July 5 Facebook post ( direct link , archive link ) includes nine slides describing supposed policy propositions from former President Donald Trump. The slides include an image of Trump along with the title "Project 2025."
“Trump has made his authoritarian intentions quite clear with his Project 2025 plan,” reads the post's caption.
It received more than 500 shares in four days.
More from the Fact-Check Team: How we pick and research claims | Email newsletter | Facebook page
Project 2025 is a political playbook created by the Heritage Foundation and dozens of other conservative groups, not Trump, who said he disagrees with elements of the effort. There are, however, numerous people involved in Project 2025 who worked in Trump's first administration.
The Heritage Foundation, a conservative think tank , collaborated with more than 100 conservative groups for Project 2025, also known as the Presidential Transition Project. The result is a more than 900-page playbook with policy recommendations for the next Republican president that reflect the think tank's goal of "(rescuing) the country from the grip of the radical Left."
Trump, however, has sought to publicly distance himself from the effort, as reported by The Washington Post .
“I know nothing about Project 2025,” Trump wrote in a July 5 Truth Social post . “I have no idea who is behind it. I disagree with some of the things they’re saying and some of the things they’re saying are absolutely ridiculous and abysmal. Anything they do, I wish them luck, but I have nothing to do with them.”
Trump didn’t specify which Project 2025 proposals he disagrees with in the statement.
Fact check : No, AP did not report Trump may face 'molestation' charges
Project 2025 said it “does not speak for any candidate or campaign” in a July 5 post on X , formerly Twitter. Its playbook is comprised of suggestions the coalition believes will benefit the "next conservative president."
“But it is ultimately up to that president, who we believe will be President Trump, to decide which recommendations to implement,” the post said.
That said, Project 2025 does involve numerous Trump allies.
Director Paul Dans , for example, was the chief of staff at the Office of Personnel Management during the Trump administration. Trump advisor Stephen Miller and the Trump campaign's National Press Secretary Karoline Leavitt also appeared in a video supporting the project’s “Presidential Administration Academy."
There is also overlap between Trump's platform and Project 2025's proposals.
The project has called for an end to illegal immigration while Trump has vowed to "carry out the largest domestic deportation operation in American history" and "terminate every open borders policy of the Biden administration ," if re-elected.
Project 2025 also supports shutting down the Department of Education , which Trump pledged to do in a 2023 campaign video .
The Heritage Foundation said in a January 2018 news release that Trump had adopted nearly two-thirds of its policy recommendations within his first year in office.
USA TODAY has debunked an array of claims about Trump, including false assertions that he selected Michael Flynn as his vice president , that a video shows “Trump Force One” buzzing a Washington-area airport after the June presidential debate and that Trump was found guilty in his hush-money trial by a jury stacked with Biden supporters .
The Facebook user who shared the post told USA TODAY it's a "logical inference" that Trump supports the project because of the number of his allies who are involved, even if he has not publicly endorsed the effort.
Thank you for supporting our journalism. You can subscribe to our print edition, ad-free app or e-newspaper here .
USA TODAY is a verified signatory of the International Fact-Checking Network, which requires a demonstrated commitment to nonpartisanship, fairness and transparency. Our fact-check work is supported in part by a grant from Meta .
Implementation Science volume 19 , Article number: 52 ( 2024 ) Cite this article
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Complex health interventions (CHIs) are increasingly used in public health, clinical research and education to reduce the burden of disease worldwide. Numerous theories, models and frameworks (TMFs) have been developed to support implementation of CHIs.
This systematic review aims to identify and critique theoretical frameworks concerned with three features of implementation; adaptability, scalability and sustainability (ASaS). By dismantling the constituent theories, analysing their component concepts and then exploring factors that influence each theory the review team hopes to offer an enhanced understanding of considerations when implementing CHIs.
This review searched PubMed MEDLINE, CINAHL, Web of Science, and Google Scholar for research investigating the TMFs of complex health interventions. Narrative synthesis was employed to examine factors that may influence the adaptability, scalability and sustainability of complex health interventions.
A total of 9763 studies were retrieved from the five databases (PubMed, MEDLINE, CINAHL, Web of Science, and Google Scholar). Following removal of duplicates and application of the eligibility criteria, 35 papers were eligible for inclusion. Influencing factors can be grouped within outer context (socio-political context; leadership funding, inter-organisational networks), inner context; (client advocacy; organisational characteristics), intervention characteristics (supervision, monitoring and evaluation), and bridging factors (individual adopter or provider characteristics).
This review confirms that identified TMFS do not typically include the three components of adaptability, scalability, and sustainability. Current approaches focus on high income countries or generic “whole world” approaches with few frameworks specific to low- and middle-income countries. The review offers a starting point for further exploration of adaptability, scalability and sustainability, within a low- and middle-income context.
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This study identified that current existing theories, models and frameworks (TMFs) focus on high income countries or generic “whole world” approaches with few frameworks specific to low- and middle-income countries.
This study explored the factors influencing the adaptability, scalability and sustainability of complex health interventions within current TMFs.
This study evaluated the applicability and feasibility of current TMF in low- and middle-income countries.
This systematic review examines the adaptability, scalability, and sustainability (ASaS) of complex health interventions (CHIs), which are increasingly used in public health, clinical research, and education to alleviate global disease burdens [ 1 ]. The effectiveness of CHIs depends on various factors, including health resources, education levels, and economic status [ 2 , 3 ].
CHIs are interventions with multiple interacting components, posing unique evaluation challenges beyond the usual practical and methodological difficulties [ 4 ].
Adaptability, scalability, and sustainability are crucial concepts in implementing CHIs, addressed through stages of evidence efficacy, scaling-up, and long-term sustainability [ 5 ]. Initial research phases focus on adapting interventions to local contexts and needs [ 6 ]. Once effectiveness is proven, the goal shifts to broader implementation, aiming for sustainability in real-world settings [ 5 ].The definitions of the ASaS is shown in the Table 1 .
Theories, models and frameworks are used extensively to advance implementation science [ 10 , 11 , 12 , 13 ], to guide the design and implementation of complex interventions, and to help in assessing their quality. The resultant models can also be used to elucidate causal mechanisms between influencing factors and to identify contextual factors associated with changes in outcomes [ 10 , 11 , 14 ]. In turn, TMFs offer a lens for the exploration of the complex fields of public health, health policy and social care [ 10 , 13 ].
Generally, a theory is:
“a set of inter‐related concepts, definitions and propositions that present a systematic view of events or situations by specifying relations among variables, to explain and predict the events or situations [ 15 , 16 ].
Simply put, theories, are closely related to models. Specially, theories are characterized as combining the explanatory alongside the descriptive, and models are defined as theories with a narrowly defined scope of explanation [ 16 ]. A framework is:
“a structure, overview, outline, system or plan consisting of various descriptive categories including concepts, constructs or variables, and the relations between them that are presumed to account for a phenomenon” [ 16 , 17 ].
Compared with theories and models, frameworks do not seek to be explanatory; rather than describe the internal relationships of concepts, they simply present the concepts [ 16 ]. However, despite some diverse characteristics, the terms “theory”, “model” and “framework” (TMF) are often used interchangeably.
However, most existing frameworks and measures for determining implementation factors and outcomes have originated in high-income nations [ 18 ]. A study indicated that although the number of frameworks related to program sustainability is increasing, these frameworks are rarely applied and evaluated in low- and middle-income countries or vulnerable communities within high-income countries. The primary reason for this phenomenon is the unique challenges faced by these countries and regions in terms of community and workplace capacities [ 19 ]. Therefore, it cannot be assumed that current TMFs are suitable for resource-limited settings [ 20 ].
Consequently, the aim of this review is to conduct a systematic review of theoretical frameworks concerned with at least one of the three ASaS concepts, to deconstruct the constituent theories, and to analyze the influencing factors within these frameworks. Another aim of this study is to assess the applicability and feasibility of these TMFs in diverse settings.
Specifically, the objectives of this review are:
To explore definitions of scalability, adaptability, and sustainability.
To identify published theoretical studies concerned with at least one of the concepts of sustainability, scalability and adaptability of complex health intervention-related frameworks and to assemble and explore relevant models and frameworks;
To explore inter-relationships between factors influencing scalability, adaptability, and sustainability of the complex health interventions;
To analyse the applicability and feasibility of these TMFs;
To appraise the methodological quality and reporting quality of the included literature.
Systematic review methods were employed to identify and select TMFs. Specifically, the BeHEMoTh procedure was used as a systematic approach by which to collect theoretical frameworks [ 10 ]. The BeHEMoTh procedure offers auditability and transparency when identifying published TMFs [ 21 ]. Specific features of the BeHEMoTh search process are outlined in Additional file 1. The search begins with a structured BeHEMoTh question. First, the researcher reviewed TMFs identified from a scoping review in order to construct a systematic search procedure for retrieving ASaS related TMFs via Google Scholar [Step 1a]. PubMed MEDLINE, CINAHL and Web of Science, were systematically searched using the same search strategy, in a process similar to a conventional systematic review search [step 1b]. Titles and abstracts were screened for TMFs using a spreadsheet with each additional instance being added to the list of TMFs previously identified via step 1 [step 2]. Named models retrieved from step 2, together with models found from scoping via Google Scholar, were then searched to retrieve additional related reports [step 3]. Searching of source references for these TMFs was used to reveal cited studies [step 4a and step 4b].
Search terms across all sources were organized within five search term groups including the three ASaS concepts (See Additional file 1). By searching for the three ASaS concepts individually rather than for their intersect, the search strategy recognises that few models involve all three factors of ASaS with many involving one or two factors.
Identified publications were imported to Endnote 9 software and duplicates were deleted. Specific inclusion criteria for factors that influence ASaS of CHIs are shown in Table 2 .
The titles and abstracts were screened, and the full papers of potentially relevant studies were obtained. Two authors independently assessed 10% of all titles and abstracts with a single reviewer then selecting full text papers for eligibility. An initial data extraction form was modified and adopted after revision. A single researcher independently extracted: (1) Study identification: year of publication, authors, name of study and name of the theories, models and frameworks; (2) Methods: study design, and study context; (3) any TMFs used; (4) Purpose of the theories, models, and framework; (5) Theories, models, and frameworks: definition, conceptual model, framework; (6) factors influencing ASaS of CHIs and inter-relationships between these concepts. These tables are shown in Additional file 3.
Quality assessment criteria for assessing reports of TMFs are not common. Three papers were identified that either develop or utilize criteria for assessing theories [ 22 , 23 , 24 ] and these papers were used to compile the following quality assessment criteria:
Is the methodology identified and justified?
Was a theoretical lens or perspective used to guide the study, with a reference provided?
Is the theoretical framework described?
Is the theoretical framework easily linked with the problem?
If a conceptual framework is used, are the concepts adequately defined?
Are the relationships among concepts clearly identified?
Are the influencing factors of concepts clearly identified?
Are the relationships among influencing factors clearly described?
Quality assessments were undertaken by a single reviewer, quality assessment judgements are reported in Additional file 4.
Given that the literature relating to TMFs derives from multiple disciplines, the researcher decided to use a narrative synthesis approach, which allows for synthesis of diverse types, designs and contexts for studies [ 25 , 26 , 27 ].
First, collected TMFs were categorized against a pre-existing classification: (1) Process models; (2) Determinant frameworks; (3) Classic theories; (4) Implementation theories; (5) Evaluation frameworks [ 16 ] (Table 3 ).
To effectively analyze the factors influencing the adaptability, scalability, and sustainability (ASaS) of complex health interventions (CHIs), this review integrates insights from multiple frameworks. Initially, the EPIS (Exploration, Preparation, Implementation, Sustainment) model was utilized, categorizing influencing factors into four key dimensions: Outer Context, Inner Context, Intervention Characteristics, and Bridging Factors. However, a more comprehensive understanding was needed, as the EPIS model alone did not fully capture the complexity of these factors.
To address this, features from the CFIR (Consolidated Framework for Implementation Research) and insights from the NASSS (Non-adoption, Abandonment, Scale-up, Spread, and Sustainability) framework and the Dynamic Sustainability Framework (DSF) were integrated. This meta-model enhancement involves expanding the descriptions within each EPIS dimension to cover additional critical elements found in these other frameworks.
Specifically, within the Inner Context, the organizational characteristics were elaborated to reflect deeper organizational dynamics affecting CHIs. In the Outer Context, the Sociopolitical Context was added, acknowledging its crucial influence on intervention outcomes. Further, the Intervention Characteristics were detailed more extensively to capture the nuanced nature of the interventions themselves.
This enriched model aims to provide a robust analytical framework that better reflects the complex interplay of factors influencing the ASaS of CHIs. By adopting this meta-model, the study offers a comprehensive theoretical foundation that underpins the examination of these complex interventions, paving the way for more targeted and effective implementation strategies in diverse settings.
Finally, the Theoretical Quality Tool, adapted from Hean et al. [ 31 ], was employed to rigorously assess the applicability of the collected (TMFs) in the context of Low- and Middle-Income Countries (LMICs).
The flowchart of the search results (Fig. 1 ) shows that the search identified 9763 studies. Following removal of duplicates and application of eligibility criteria, 37 studies remained for inclusion in the review. 25 studies provide macroscopic TMFs for CHIs [ 5 , 6 , 7 , 8 , 9 , 30 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 ] worldwide. A further seven included TMFs [ 50 , 51 , 52 , 53 , 54 , 55 , 56 ] that were developed in high-income countries and only five studies [ 21 , 57 , 58 , 59 , 60 ] targeted LMICs.
PRIMA diagram of article selection
Overall, 28 [ 5 , 6 , 7 , 8 , 9 , 21 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 48 , 49 , 50 , 55 , 57 , 58 , 61 ] of the 37 studies describe macroscopic TMFs and nine studies [ 30 , 47 , 51 , 52 , 53 , 54 , 56 , 59 , 60 ] describe TMFs for specific relevant interventions. Categorising these according to the five categories of Per Nilsen's schema (Table 3 ) reveals that 14 of the 37 TMFs are process models, 14 are determinant frameworks, one is classic theory, one is implementation theory, and seven are evaluation frameworks (See Additional file 5). One classic theory and one implementation theory are included. The Detailed classification for collected TMFs is described in Table 4 .
All 37 included studies reported at least two out of the three concepts of ASaS, and the specific concepts involved in each study. (See Table 5 ). Definitions of ASaS found in the included studies are shown in the Additional file 2.
Diverse TMFs support a strong correlation between the three ASaS concepts and the implementation process. Twenty-five of the TMFs explicitly mentioned implementation of CHIs; while the remaining ten did not [ 6 , 8 , 21 , 39 , 40 , 44 , 54 , 55 , 56 , 62 ].
This review confirms the interconnectedness of adaptability, scalability, and sustainability in the implementation of complex health interventions (CHIs). The findings suggest that adaptability is crucial during the initial stages of CHI deployment, determining the potential for effective and cost-efficient implementation. As the intervention progresses, scalability becomes critical, ensuring that strategies effective on a smaller scale can be expanded to broader populations and regions. Ultimately, sustainability is achieved in the final stages, focusing on maintaining the benefits of the intervention over time and making necessary adjustments based on ongoing feedback and changing conditions.
In essence, the successful scaling and long-term sustainability of CHIs fundamentally depend on their initial adaptability. This streamlined approach highlights the critical progression from adaptability through scalability to sustainability, without delving into the specifics of various models and frameworks.
This study collected and analyzed factors affecting the adaptability, scalability, and sustainability (ASaS) of complex health interventions (CHIs), systematically categorizing them into four distinct categories: outer context, inner context, intervention characteristics, and bridging factors. This classification helps clarify the various factors that influence the implementation of health interventions.
While all these factors impact the three concepts of ASaS, some have particularly close relationships with specific ASaS concepts. Subsequent sections will explore these factors in detail, emphasizing those closely linked to individual ASaS concepts. This approach highlights the multidimensionality of these factors and their varying impacts on the adaptability, scalability, and sustainability of CHIs. The overview of the factors influencing the ASaS is shown in the Table 6 .
Name of influencing factors, suggested definition, frequency of influencing factors of Outer context is shown in Table 7 .
This study has identified multiple studies highlighting how sociopolitical factors deeply influence the adaptability, scalability, and sustainability (ASaS) of complex health interventions (CHIs) [ 8 , 30 , 35 , 37 , 39 , 42 , 44 , 47 , 49 , 50 , 51 , 52 , 53 , 54 , 58 , 59 , 60 , 64 ]. These factors, including religion [ 58 ], ethics [ 39 , 56 ], legislation [ 30 , 35 , 39 , 44 , 54 , 58 , 59 , 64 ], norms or regulations [ 7 , 21 , 35 , 38 , 49 , 54 , 56 , 58 ], and policies [ 6 , 7 , 9 , 21 , 35 , 37 , 38 , 39 , 44 , 50 , 51 , 54 , 56 , 57 , 59 ], play a critical role in shaping health outcomes and addressing healthcare disparities. The influence of sociocultural factors such as common traditions, habits, patterns, and beliefs was also evident across different populations [ 35 , 37 , 38 , 39 , 44 , 50 , 52 , 54 , 57 , 58 , 62 ].
Interorganizational networks bridge full-scale relationships across organizations [ 65 ], and it was found to significantly enhance the implementation of CHIs, enabling better adaptation to local contexts and sustainability at lower costs through effective resource sharing and communication.
Also, the role of funding was another major factor discussed, highlighting its critical importance for providing necessary resources such as training, materials, and health services [ 66 ]. Nineteen of the identified models or frameworks emphasize fiscal support prioritized in implementation [ 6 , 7 , 8 , 9 , 21 , 30 , 34 , 35 , 36 , 38 , 39 , 44 , 45 , 50 , 54 , 55 , 58 , 59 , 64 ].
Three of the 37 studies identify client advocacy as an important influencing factor [ 9 , 45 , 50 ]. During implementation client advocacy assists healthcare workers, participants and their families in navigating the healthcare system [ 67 ].
Finally, 16 of the 37 studies emphasize leadership [ 6 , 21 , 30 , 35 , 36 , 40 , 42 , 43 , 44 , 45 , 50 , 51 , 56 , 57 , 58 , 59 ]. Specific subgroups may offer either approval or conflict. Strong leadership can promote effective use of resources while encouraging personnel to work towards a common goal.
Name of influencing factors, suggested definition, frequency of influencing factors of Outer context is shown in the Table 8 .
Organizational characteristics influence the process of implementing complex health interventions (CHIs) through structures and processes within organizations. These characteristics encompass ten influencing factors including absorptive capacity [ 6 , 8 , 9 , 21 , 36 , 37 , 40 , 44 , 50 , 51 , 52 , 56 , 57 , 59 , 64 ], organizational readiness [ 8 , 30 , 50 , 51 , 52 ], structure [ 6 , 7 , 35 , 38 , 40 , 44 , 49 , 51 , 52 , 59 , 64 ], values or visions [ 35 , 37 , 40 , 43 , 44 , 51 , 59 ], working environment [ 6 , 7 , 8 , 9 , 41 , 45 , 50 , 51 , 54 , 56 ], tension for change [ 6 , 49 , 51 , 53 ], organization culture [ 6 , 35 , 40 , 43 , 50 , 58 ], leadership [ 6 , 21 , 35 , 36 , 40 , 42 , 43 , 44 , 45 , 50 , 51 , 56 , 57 , 58 , 59 ], credibility and reputation [ 43 ]. The adaptability, scalability, and sustainability (ASaS) of CHIs are significantly dependent on these organizational elements.
Organisations with strong organisational power may be likely to implement CHIs because they have stronger leadership and more frequent communication than those with weak or decentralised organisational structures [ 68 ].
Readiness for change
In addition, strong organisations are prepared and aware of possible encountered changes and can adjust their strategies and approaches of working in time to enable CHIs to be carried out well. Readiness for change is related to other factors including organisational culture, and individual attitudes [ 69 , 70 , 71 , 72 ].
Absorptive capacity
During the exploration and preparation phases of a CHI, an organisation's absorptive capacity (the ability to identify, assimilate, transform, and use external knowledge, research and practice [ 73 ]), readiness for change and receptive environment exert a significant impact on the adaptability of CHIs.
Individual adopter or provider characteristics
Individual adopter or provider characteristics include participants’ personal characteristics, age, race/ethnicity, education, training, foundation subjects, professional experience, adaptability, personal values and goals, and personal character creative ability.
Fourteen included studies emphasise how the CHI is accepted and scaled-up by participants and health care workers [ 6 , 7 , 8 , 34 , 35 , 36 , 41 , 45 , 47 , 51 , 53 , 54 , 56 , 58 ]. In parallel to the organisational level, individual ability or capacity [ 6 , 35 , 44 , 51 , 53 , 56 , 57 , 64 ], training or education [ 7 , 8 , 35 , 36 , 40 , 51 , 52 , 56 ], and tenacity for change [ 6 , 51 , 53 ] constitute important factors. CHIs are more easily adapted and diffused when led by experienced and leaders [ 6 , 21 , 35 , 36 , 40 , 42 , 43 , 44 , 45 , 50 , 51 , 56 , 57 , 58 , 59 ] with common visions or views [ 6 , 35 , 51 , 53 , 56 , 60 , 64 ]. In addition, race [ 35 , 50 ], spoken language [ 35 , 50 , 52 ] and individual culture [ 35 , 53 , 56 , 59 ] are considered to be vital influencing factors. Specifically, when there is a high degree of fit between the norms and values of the individual, organisation and CHIs, individuals may find that they achieve higher efficacy when implementing CHIs [ 64 ].
As mentioned above, 16 of the 37 included studies emphasize leadership [ 6 , 21 , 30 , 35 , 36 , 40 , 42 , 43 , 44 , 45 , 48 , 50 , 51 , 56 , 57 , 58 , 59 ].
CHIs require sufficient, well-trained healthcare workers. Fourteen of the 37 studies list staffing as an important factor in their TMFs [ 7 , 30 , 34 , 35 , 36 , 37 , 43 , 44 , 45 , 50 , 51 , 52 , 56 , 64 ]. Job candidates may be selected so that their knowledge, skills, competencies, and attitudes [ 74 ] match the requirements of the CHI.
Supervision, monitoring and evaluation
Supervision, monitoring and evaluation refers to the collection, storage, analysis and use of data to assess whether complex interventions are achieving their intended objectives, and further influences improvement, policy development and advocacy of complex intervention [ 75 ]. Nine of the 35 studies argue for the vital role of monitoring and evaluation in providing an effective approach by which to assess the effectiveness of complex interventions [ 21 , 30 , 40 , 43 , 44 , 50 , 51 , 58 , 64 ].
The characteristics of the intervention itself is also an important factor. Specifically, the physical and community environment, the cost of the intervention and access to resources (8 studies) [ 6 , 21 , 30 , 34 , 38 , 51 , 52 , 56 ] and the source of funding all exert a direct impact. Project champions are committed to supporting and promoting the implementation of CHI, along with a strong belief in the value of carrying out CHIs [ 76 ]. The factors within intervention characteristics is shown in the Table 9 .
The included frameworks attest to how the characteristics of the CHI decide whether an intervention can be adapted, scaled-up and sustained [ 6 , 8 , 33 , 36 , 47 , 51 , 53 ]. Although researchers hope that CHIs can be adapted and conducted as quickly as possible, it takes time for both healthcare providers and participants to adapt to new interventions [ 77 ]. Also, when interventions change significantly within a short period of time, the lack of sufficient time to adapt to the intervention and adjust to relevant cultural factors prevent staff and participants from adopting a new CHI [ 78 ].
Factors influencing the inter-relationship of outer and inner context are described as “bridging factors” in the EPIS framework. Bridging factors include community engagement and Purveyors/Intermediaries.
Twelve studies stress the importance of the community. Development of complex interventions within a community may be facilitated when they utilise existing community resources, available structures and staff, reducing dependence on external funding [ 21 ]. For example, community members were proud to participate in a project to improve malaria prevention through insecticide-treated mosquito nets and thereby contribute to disease control within their community. Consequently, the project was speedily adapted, replicated and scaled-up locally [ 79 ]. The community function is also affected by socio-political factors [ 80 ]. If the visions and beliefs of the policy are inconsistent with community objectives, the policy hinders spread and sustainability even where the community possesses powerful leadership, project champions and sufficient resources [ 80 , 81 ].
Purveyors/Intermediaries take on a critical bridging role for key processes in the implementation of CHIs [ 45 ]. Purveyors, who may be individuals, groups or communities, aim to facilitate the effective and sustainable implementation of CHIs [ 82 ]. Intermediaries provide consultancy and training services to governments, organisations, etc., and also develop and implement different health-services and projects for them [ 82 ]. They also provide monitoring, support, quality improvement and evaluation services at the end of the project [ 82 ]. The factors within bridging factors is shown in the Table 10 .
This study employs the Theoretical Quality Tool, adapted from Hean et al. [ 31 ], to rigorously assess the applicability of various Theoretical Models and Frameworks (TMFs) in the context of Low- and Middle-Income Countries (LMICs). The detailed outcomes of this assessment are presented in the Additional file 6. The summary table highlights the applicability and feasibility of TMFs in LMICs.
Of the 37 TMFs reviewed (two studies identify EPIS), seven demonstrate high applicability and feasibility, readily integrating into LMIC healthcare environments without necessitating significant overhauls. For example, models like the AIDED and NPT are readily implementable in LMICs due to their practicality and context-sensitive design. They integrate seamlessly into existing healthcare systems, offering solutions without the need for extensive system overhauls, crucial in resource-limited environments. Twenty-five TMFs require adaptations to align with the local conditions of LMICs, entailing modifications to fit cultural, economic, and healthcare infrastructure nuances. For example, the EPIS framework, CFIR framework, PRISM Model and Chronic Care Model, though broadly applicable, need customization to fit the unique cultural, economic, and healthcare infrastructures of LMICs.
For the remaining five TMFs, their inherent theoretical complexity and the fact that some were specifically designed for High-Income Countries (HICs) pose significant barriers to adoption in in Low- and Middle-Income Countries (LMICs). This finding highlights an important disconnect between their foundational assumptions and the practical realities of healthcare systems in LMICs. The evaluation outcomes of the applicability and feasibility of the collected 37 TMFs are shown in the Table 11 .
This theoretical systematic review identified common features and differences across 37 TMFs associated with ASaS.
All identified TMFs emphasize the importance of one or more of the three ASaS concepts. These frameworks aim to enable CHIs to adapt to new contexts and populations, scale up interventions, and ensure long-term effectiveness. The components of different TMFs share broadly similar descriptions, even if the terminology varies. For example, the EPIS framework divides the implementation process into four phases: exploration, preparation, implementation, and sustainment whereas Sarma’s framework [ 5 ] describes three domains: i: evidence – efficacy to effectiveness; ii: Scaling-up; and iii: sustainability. A further study [ 36 ] describes four stages 1. Training (dissemination); 2. adoption (planning); 3. implementation; 4. practical improvement and two key points (preparation and maintenance).
In the EPIS framework, during exploration and preparation, adaptability is considered to determine whether the complex intervention can be conducted effectively with affordable cost. Domain I of Sarma’s framework [ 5 ] includes the four vital components of intervention sources, evidence strength and quality, relative advantages, adaptability and complexity. The Framework - oral health [ 36 ] emphasizes adoption within the second stage. Hence, these three stages have the similar key components. The EPIS framework describes how a pilot study is further implemented across diverse participants and areas, which is similar to Domain ii: Scaling-up in Sarma’s framework [ 5 ] and the implementation stage in Framework - oral health [ 36 ]. Finally, the sustainment stage in EPIS framework, Domain iii: sustainability in Sarma’s framework [ 5 ] and the maintenance point in Framework - oral health [ 36 ] all convey a shared understanding of sustainability.
Similar stages may be presented in a different order within various models, reflecting the inherently multi-stage and non-linear nature of CHI implementation. Significant differences across different TMFs primarily relate to influences on ASaS. Furthermore, even when different TMFs use the same terminology to describe influencing factors, the meanings may differ due to the inherent complexity and dynamics of these factors.
The TMFs reflect how CHIs and associated influencing factors do not operate in isolation, but are non-linear, interacting and interdependent. Some influencing factors appear across multiple studies. For example, researchers share a consensus about the importance of funding [ 6 , 7 , 8 , 9 , 21 , 34 , 35 , 36 , 38 , 39 , 44 , 45 , 50 , 54 , 55 , 58 , 64 ]. Some studies emphasise adequate and sustained financial support from governments and foundations as prerequisite to the sustainability and spread [ 5 , 44 , 50 , 61 ], while Sarma [ 5 ] recognizes the need to sustain interventions in the absence of adequate funding [ 21 ]. In addition, the sociopolitical context, leadership and organizational characteristics are repeatedly mentioned as essential components for implementation. Furthermore, all the factors mentioned in the literature are bi-directional; the same influencing factor may act differently under diverse conditions, either as a facilitator or as a hindrance.
To be specific, first, in terms of the outer context, strong leadership can facilitate effective use of resources while encouraging personnel to work towards a common goal. Also, sociopolitical factors covers ethical considerations [ 39 , 56 ], legislation [ 35 , 39 , 44 , 54 , 58 , 64 ], norms or regulations [ 7 , 21 , 35 , 38 , 54 , 56 , 58 ], policies [ 6 , 7 , 9 , 21 , 35 , 37 , 38 , 39 , 44 , 50 , 51 , 54 , 56 , 57 ], and religion [ 58 ]. Legislation and policies not only guide, and often guarantee, complex interventions at the macro level, but also, at the empirical level, provide a basis for adapting CHIs to the local environment thereby making interventions suitable for scale up and long term sustainment [ 35 , 39 , 44 , 54 , 58 , 64 ]. High quality interorganizational communication contributes to the implementation and sustainability of CHIs [ 83 ]. Additionally, weak leadership exerts a negative impact on the management of the organisation, funding applications and the recruitment of staff.
Leadership remains an important factor in relation to the inner context. Given that complex interventions are often run by the state, an organisation or a group, strong leadership can facilitate complex interventions. Also, the organisational culture, the vision/belief and the structure of the organisation interact with each factor and are influenced by funding, leadership and staffing.
Strong leadership needs to be accompanied by a structured organisation with a common vision in order to achieve the objectives of complex interventions. People as the carriers of culture, organisation, professional and personal attitudes, norms, interests and affiliations [ 84 ] also fulfil an important role. Individual adopter or provider characteristics are important influencing factors. When people within the organisation are aligned with the organisation's philosophy and culture, along with sufficient financial support, strong leadership and effective supervision, adaptation, scale up and long-term sustainment become possible for CHIs. Finally, intervention factors are influenced by both the outer context and the inner context, and bridging factors serve to unite the outer context, the inner context, and the intervention factors.
Factors that influence complex interventions are dynamic in both temporal and geographical terms. The role of these factors may change over time [ 85 ]; anticipated barriers may become facilitators [ 85 ]. For example, in the early stages of an intervention, individual adopters may exhibit skepticism and distrust, presenting a barrier to CHI delivery. However, in later stages, if the intervention proves effective, participant attitudes may shift, motivating them to cooperate and thus becoming facilitators. Similarly, in the early stages, newly recruited or local staff may be unfamiliar with the intervention, posing a hindrance. Conversely, as staff become familiar with the intervention, they are better equipped to implement it, thereby becoming facilitators.
Identical influencing factors may have different effects in various geographical and national contexts. For example, women are generally considered a vulnerable group worldwide, particularly in LMICs, where they tend to have lower income and social status compared to men, making it difficult for them to access better health care resources [ 86 ]. However, in the matrilineal community in Indonesia, women occupy similar or even higher social status than men, with a cultural tradition of controlling family finances [ 87 ]. Therefore, in this context, gender and culture may facilitate interventions, especially maternal and child health related interventions. In relation to funding, reliable sources of funding help to sustain interventions [ 5 ], and one of the challenges to sustainability is the lack of long-term available funding [ 21 ]. In summary, this systematic review offers a comprehensive understanding of factors influencing ASaS and provides a theoretical framework for effective CHIs in the future.
This is the first systematic review of ASaS related TMFs of CHIs. By focusing on the three factors of adaptability, sustainability and spread the review has been able to explore complex interactions of each with each other and with other important factors.
Additional file 2 consolidates definitions of scalability, adaptability and sustainability as identified across the included studies. It is noticeable that “sustainability has evolved from being considered as the endgame of a translational research process to a suggested 'adaptation phase’ that integrates and institutionalizes interventions within local organizational and cultural contexts.” [ 7 ]
This literature argues that sustainability is, in fact, a manifestation of adaptability, and that the two concepts are closely related.
This review reveals the scarcity of theoretical models for LMICs. The review identified four main categories of theoretical models, (i) the generic TMFs (e.g. RE-AIM and CFIR), with no obvious geographical target (26/37); (ii) tailored TMFs developed by some high-income countries (e,g. [ 52 , 53 , 56 ]. for local needs (6/37); (iii) adapted TMFs (e.g. EPIS and Framework of Dissemination in Health Services Intervention Research), originally designed for high-income countries but now adapted to CHIs worldwide; (iv) TMFs specific to low and middle income countries (5/37) (e.g. [ 21 , 57 ]). 85.7% of the included theories are either generic or specific to high-income countries, with a lack of TMFs specifically targeted at LMICs. As a result of this literature review the team have proceeded to develop a framework for Adaptability, Scalability and Sustainability that is suited for a low- and middle-income country context.
Thirty seven studies explore at least one of the concepts of sustainability, scalability and adaptability. However, no previous studies have explored all three ASaS concepts within a single TMF. Although some studies invoke the need to explore influencing factors and correlation among ASaS, no studies have actually conducted this research.
The meta-framework provides a comprehensive structure to explore the complexities of CHI implementation, emphasizing the interplay among four critical domains: outer context, inner context, intervention characteristics, and bridging factors.
In the outer context, the interplay between strong leadership, sociopolitical factors, and interorganizational networks is crucial. Strong leadership promotes resource optimization and strategic alignment toward CHI goals, essential for ASaS [ 35 , 39 , 44 , 54 , 58 , 64 ]. Sociopolitical factors, including legislation, policies, and norms, provide a regulatory framework that guides the adaptation of CHIs to local settings, enhancing their feasibility and long-term integration [ 83 ]. Additionally, robust interorganizational communication facilitates effective adaptation of CHIs to local contexts, potentially lowering costs and enhancing sustainability.
Within the inner context, organizational culture, structure, and leadership significantly interact, affecting CHI outcomes. Strong, visionary leadership is crucial for fostering an organizational culture that supports CHIs and aligns with broader intervention goals [ 84 ]. The organization's structure further influences the implementation of these interventions, with well-structured organizations likely to achieve better scalability and sustainability. Additionally, the characteristics of individual providers and adopters play a critical role, impacting their ability to effectively implement and sustain CHIs.
The characteristics of the intervention itself directly impact its implementation. Factors such as the intervention's complexity, cost, resource requirements, and specific design elements determine the ASaS especially for the stages of adaptability and scalability [ 6 , 21 , 30 , 34 , 38 , 51 , 52 , 56 , 59 ]. Support from project champions and stakeholder involvement are crucial in facilitating the implementation process, ensuring that the interventions are well-supported and aligned with stakeholder expectations [ 8 , 21 , 34 , 36 , 37 , 40 , 44 , 49 , 50 , 56 , 60 ].
Bridging factors like community engagement and the role of purveyors/intermediaries are vital for linking the outer and inner contexts of CHIs. Community engagement leverages local resources and capacities, which is essential for the localized adaptation and sustainability of interventions [ 8 , 9 , 21 , 30 , 34 , 38 , 42 , 44 , 45 , 54 , 56 , 58 ]. Purveyors and intermediaries facilitate the transfer of knowledge and best practices, enhancing the overall effectiveness and reach of CHIs [ 45 ]. These bridging roles ensure that interventions are not only well-integrated within communities but also maintain fidelity to their objectives and outcomes over time.
The lack of specifically designed TMFs for LMICs presents significant challenges in effectively implementing complex health interventions (CHIs) in these settings. Evaluating existing TMFs reveals a gap in their suitability and feasibility for application within the unique healthcare environments of LMICs.
Of the 37 TMFs assessed, many were found to require adaptations to align with the local conditions of LMICs, necessitating modifications to fit cultural, economic, and healthcare infrastructure nuances. For instance, frameworks such as EPIS, CFIR, PRISM Model, and Chronic Care Model, though broadly applicable, need customization to fit the unique contexts of LMICs.
Five of the TMFs reviewed were identified as inherently complex and primarily designed for high-income settings, posing substantial barriers to their adoption in LMICs. This highlights a critical disconnect between the foundational assumptions of these models and the practical realities of healthcare systems in LMICs, which face challenges such as limited resources, differing disease burdens, and varied healthcare delivery systems.
Despite these challenges, some models demonstrate higher applicability and feasibility. For example, the Dynamic Sustainability Framework (DSF) and the AIDED model are noted for their practicality and context-sensitive design, aligning with the continuous adaptation and learning required in LMICs. These models integrate seamlessly into existing healthcare systems, offering solutions without the need for extensive system overhauls, which is crucial in resource-limited environments.
The findings underscore the need to develop or adapt existing TMFs specifically tailored to the conditions of LMICs. This involves considering local healthcare practices, resource limitations, and cultural factors to ensure that the frameworks are both applicable and feasible in supporting the effective implementation and sustainability of CHIs in these settings.
This systematic review retrieved relevant literature through a comprehensive search across four databases. Only studies published in English were included, potentially missing those from the grey literature. Identifying relevant implementation TMFs proved challenging due to the complex and diffuse terminologies used in this field. Exhaustive lists of synonyms would have been prohibitive, resulting in lack of specificity and numerous false positives. The authors sought an optimal balance between sensitivity and workload. Although the included studies were evaluated using a quality assessment tool, the risk of bias remains, particularly since only one author was responsible for data extraction.
Furthermore, although this review has identified how influencing factors interact, no clear theoretical model charts the specific TMFs, routes, and pathways from the influencing factors to the ASaS of CHIs. Finally, concepts such as acceptability, fidelity, and feasibility, are recognized as important features of CHIs [ 88 ] but fell outside the remit of this review.
Only one classic theory and one implementation theory are included. There are two possible reasons. Classical theories are borrowed from such disciplines as psychology, sociology and organisational development (e.g. the Diffusion of Innovation theory [ 89 ]. Similarly. the Health Belief Model was published in 1950 [ 90 ] and the Theory of Planned Behavior in the late 1980s [ 91 ]. Given that inclusion requires publication after 2000, many classic theories predate the study period. On the other hand, other theories, such as the implementation climate theory [ 92 ], may not be conceptually related to ASaS, resulting in their exclusion. The Detailed classification for collected TMFs is described in Table 4 .
This review synthesizes 37 TMFs that document factors influencing the ASaS of CHIs. It confirms the wide variety of definitions used for adaptability, scalability, and sustainability within current TMFs, which typically do not include all three components. Current approaches focus on high-income countries or generic “whole world” approaches, with few frameworks specific to low- and middle-income countries. Numerous attempts have been made to describe and explore the interrelationships between implementation components. Of these, the EPIS and CFIR frameworks seem to possess the greatest inherent value, particularly within a model consisting of outer context, inner context, intervention characteristics, and bridging factors. This review offers a starting point for further exploration of adaptability, scalability, and sustainability, particularly within a low- and middle-income context.
All data cited in this review derives from published papers and therefore already available.
Adaptability, scalability and sustainability
Capability, Opportunity, Motivation and Behaviour
Evidence-based practice
Exploration, Preparation, Implementation, Sustainment (EPIS) framework
Low- and middle- income countries
Medical Research Council
Theory, model and framework
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Sun, L., Booth, A. & Sworn, K. Adaptability, Scalability and Sustainability (ASaS) of complex health interventions: a systematic review of theories, models and frameworks. Implementation Sci 19 , 52 (2024). https://doi.org/10.1186/s13012-024-01375-7
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Plant carbon (C) concentration is a fundamental trait for estimating C storage and nutrient utilization. However, the mechanisms of C concentration variations among different tree tissues and across species remains poorly understood. In this study, we explored the variations and determinants of C concentration of nine tissues from 216 individuals of 32 tree species, with particular attention on the effect of wood porosity (i.e., non-porous wood, diffuse-porous wood, and ring-porous wood). The inter-tissue pattern of C concentration diverged across the three porosity types; metabolically active tissues (foliage and fine roots, except for the foliage of ring-porous species) generally had higher C levels compared with inactive wood. The poor inter-correlations between tissue C concentrations indicated a necessity of measuring tissue- and specific-C concentrations. Carbon concentration for almost all tissues generally decreased from non-porous, to diffuse-porous and to ring-porous. Tissue C was often positively correlated with tissue (foliage and wood) density and tree size, while negatively correlated with growth rate, depending on wood porosity. Our results highlight the mediating effect of type of wood porosity on the variation in tissue C among temperate species. The variations among tissues were more important than that among species. These findings provided insights on tissue C concentration variability of temperate forest species.
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We thank Huimin Song, Danyang Yuan, Di Liu for their help in field sampling, and Yanpeng Li for drawing the correlation matrix figure. The Mudanjiang Forest Ecosystem Research Station provided the logistic support.
Jun Pan and Jing Zhang have equally contributed.
Center for Ecological Research, Northeast Forestry University, Harbin, 150040, People’s Republic of China
Jun Pan, Jing Zhang, Xingchang Wang, Xiuwei Wang, Xiankui Quan, Chuankuan Wang & Xiaochun Wang
Key Laboratory of Sustainable Forest Ecosystem Management, Ministry of Education, Northeast Forestry University, Harbin, 150040, People’s Republic of China
Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, 510650, People’s Republic of China
University of Chinese Academy of Sciences, Beijing, 100049, People’s Republic of China
National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China, Guangdong Key Laboratory of Integrated Agro-Environmental Pollution Control and Management, Institute of Eco-Environmental and Soil Sciences, Guangdong Academy of Science, Guangzhou, 510650, People’s Republic of China
Heilongjiang Institute of Ecology, Heilongjiang Academy of Forestry, Harbin, 150040, People’s Republic of China
Yankun Liu, Yulong Liu & Yunfei Diao
Correspondence to Xingchang Wang .
Publisher's note.
This work was supported by the National Natural Science Foundation of China (32171765).
The online version is available at https://link.springer.com .
Corresponding editor: Tao Xu.
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Pan, J., Zhang, J., Wang, X. et al. Variations and determinants of tissue carbon concentration of 32 sympatric temperate tree species. J. For. Res. 35 , 113 (2024). https://doi.org/10.1007/s11676-024-01764-0
Received : 28 October 2023
Accepted : 06 May 2024
Published : 20 July 2024
DOI : https://doi.org/10.1007/s11676-024-01764-0
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Three graduate students from McGill University's Department of Integrated Studies in Education (DISE) have been honoured with prestigious fellowships and awards for their international research endeavours.
Renee Davy , a PhD candidate in Educational Studies, is a 2023 recipient of the International Doctoral Research Awards (IDRA). Funded by the International Development Research Centre (IDRC), and managed by Universities Canada, the IDRA aims to enhance research skills in Canada and the Global South, with the goal of improving the lives of people in the developing world. In 2023, 25 doctoral students from 12 Canadian schools each received up to $20,000 in awards. Her project entitled Transforming Writing Instruction: Engaging Marginalized Youth in a Community Publishing Approach to Writing explores how marginalized youth’s engagement with community writing and grassroots publishing can shape their social and academic identities. Using a participatory action research approach, her work aims to challenge the deficit discourse surrounding marginalized youth and their language and literacy development. Renee’s research is being supervised by Dr. Amir Kalan .
Sitong Wang , a PhD candidate in Educational Studies, has been awarded the Graduate Mobility Award, which encourages graduate students to study and conduct research abroad as part of their McGill degree program by defraying part of the cost of the international experience. Titled “Discovering the Reading Subject”: Reducing Linguistic Prejudice in Writing Assessment in Academic Writing, focuses on reducing linguistic prejudice in writing assessment. This award enables Sitong Wang to collect material and data to examine writing course outlines, institutional language policies, and other relevant documents from universities in China. This research contributes to a thorough analysis and comparison of pedagogical methodologies and materials across universities in diverse countries, helping to determine the ubiquity of linguistic prejudice in writing education and thereby addressing Wang's research questions. Sitong Wang's research is being supervised by Dr. Amir Kalan .
Chama Laassassy , an MA student in Second Language Education, has been selected as an incoming young leader for the 2024-25 Pathy Foundation Fellowship at the Coady Institute. This prestigious 12-month fellowship, supported by the Pathy Family Foundation, provides each Fellow with up to $40,000 in funding to implement a self-designed initiative. Chama Laassassy's initiative, ⵉⵙⵡⵉ | ISWI aims to support youth at a high risk of school abandonment in Nador, Morocco (الناظور, المغرب). This project seeks to create a supportive environment for young people, helping them develop skills and opportunities that promote their personal and professional growth. offers community-focused experiential learning opportunities for graduating students. Chama Laassassy is in the final year of her MA program, focusing her research on the impact of outside-of-the-classroom language practice on language learning. Her commitment to fostering sustainable positive social change has earned her this important fellowship. Chama Laassassy's research is being supervised by Dr. Susan Ballinger . Learn more about the Pathy Foundation Fellowship .
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Write specific aims that test a single, overarching hypothesis, and not individual aims connected to their own hypotheses. Note: Depending on the grant you are seeking, this rule may not be possible or desirable. For example, if you are applying for an R01 grant in health services/outcomes research, the typical grant in this area has a data collection project at its core that often addresses ...
Draft Specific Aims. After you have decided the area of research to pursue, start thinking about your planned experiments by first drafting objectives, known in NIH lingo as Specific Aims. Be sure you can complete your Aims within the typical timeframe for your chosen Notice of Funding Opportunity (NOFO). For an R01, that's typically four to ...
Guide to Specific Aims Page for NIH Application Source: NIH Grant Applications- The Anatomy of a Specific Aims Page by Michelle S. LINK. The Specific Aims section is the most vital part of any NIH grant application. In this section, you must quickly gain the reviewers' trust and confidence while simultaneously convincing them that your work is
Steps to Success. Step 1: Develop and Refine Your Research Idea. • Define the research niche you are systematically trying to develop that will move the field forward. • Collect and critically analyze background information. • Generate a preliminary idea that is pertinent to your research problem.
Grant writing starts with the iterative development of a Specific Aims page. The Aims page serves as a concept sheet with project milestones, hypotheses, and the most important elements of the approach.[] This page also serves as a master plan for the research proposal and ideally engages the reader as an advocate during review.
The goal of this template is to help you focus your aims, one vital component of writing a successful proposal. This template is derived directly from R01's of mine that were ... Specific Aims In the template below, I use examples from a proposal of mine that was ... proteomic research is focused on identifying post-translational modifications
The Anatomy of a Specific Aims Page Release Date: Aprit 09, 2015 Category: Scientific Grant Writing Author: Michelle S., Ph.D., E.L.S. The Specific Aims section is the most vital part of any NIH grant application. In this section, you must quickly gain the reviewers' trust and confidence while simultaneously convincing them that your work is
Outlining Specific Aims. Step 1: Determine whether your research questions are exploratory (hypothesis-generating) or confirmatory (hypothesis-testing). If confirmatory, make sure the hypotheses are focused, testable, built on a solid scientific foundation, and important. Step 2: Draft aims to generate and/or test the hypotheses feasibly within ...
Research aims are relatively broad; research objectives are specific. Research aims focus on a project's long-term outcomes; research objectives focus on its immediate, short-term outcomes. A research aim can be written in a single sentence or short paragraph; research objectives should be written as a numbered list. How to Write Aims and ...
the research if the grant is funded. Some people write their Specific Aims first and then develop a hypothesis; others do the reverse. The correct method will depend on the approach that works best for you and your proposed research. A strong hypothesis should be well-focused and testable by the Specific Aims and experiments.
Research Aims: Examples. True to the name, research aims usually start with the wording "this research aims to…", "this research seeks to…", and so on. For example: "This research aims to explore employee experiences of digital transformation in retail HR.". "This study sets out to assess the interaction between student ...
A specific aim outlines how the researcher will address the study's primary goal or objective. They are typically crafted using action-oriented verbs, such as "to determine", "to compare", or "to estimate". Specific aims can be exploratory or confirmatory, intended to either generate or test a hypothesis, respectively.
Writing the actual aims of your research. And then describing the outcomes of the project. The goal of your aims section is to grant your reviewers a full picture of what you'll do to achieve your overall project objective. Then, in a few short sentences at the end, you describe the impact you expect to have. In other words, your aims are ...
Team's qualification and research environment: Specific aims: Major variables in each aim linked to gap: ... This article provides a recipe for writing an effective specific aims page using a simple four paragraph structure and gives formatting and style recommendations. It is ideal to optimize aims pages with readers who are educated ...
es important cellular pathways including gene expression, proliferation, apoptosis, and polarity. Over the years, Tax has proven to be a valuable model system in which to interrogate cellular. rocesses, revealing pathways and mechanisms that play important roles in cellular transformation. Although the Tax oncoprotein has been shown to ...
Write a draft of your Specific Aims. Write your Research Strategy. Start with your Significance and Innovation sections. Then draft the Approach section considering the personnel and skills you'll need for each step. Evaluate your Specific Aims and methods in light of your expected budget (for a new PI, it should be modest, probably under the ...
Paragraph 3: Specific Aims • Aims must test all parts of your central hypothesis • Aims should flow logically, but not be dependent • Brief, informative, attention getting "headlines" to convey why that part of the research is being proposed (not what is being done) • Should be global and open-ended to allow for alternative
The writing of effective research aims and objectives can cause confusion and concern to new and experienced researchers and learners. This step in your research journey is usually the first written method used to convey your research idea to your tutor. Therefore, aims and objectives should clearly convey your topic, academic foundation, and ...
Specific Aims Page Checklist. I describe the underlying science to the extent needed for my reviewers. I give a rationale for choosing the topic and approach. I tie the project to my preliminary data and other new findings in the field. I explicitly state my hypothesis and why testing it is important. My aims can test my hypothesis and are logical.
Specific Aims: research steps for testing your hypothesis or accomplishing your objective. Background and Significance: concise description outlining the important need addressed by your research, its scientific merit, and the impact of the research to the field of science and to public health (tailored to your research focus) Preliminary ...
The first half of the aims page should cover key background information, highlighting the product, its significance, and innovation. The second half of the aims page should state the specific aims and milestones to be completed. Applicants are only allowed one-page for their specific aims. In this PLAN series, prior SBIR/STTR awardees with a ...
Writing objectives. The objectives describe how you would achieve your research aim. You can do this through the following steps, The first one to two objectives can be applied to the literature review. (Verbs to be used: investigate, examine, study) One objective can be applied to the methodology portion.
The Specific Aims (for NIH) or Objectives (NSF) are the key to what you are proposing. You want them to be not only clearly understandable to your reviewer (right?), but also captivating and interesting. It seems like a straight-forward writing goal, but unfortunately, I've seen many people wander off into confusing, overly-detailed, or just plain
Beginner's Guide to Research. Most professors will require the use of academic (AKA peer-reviewed) sources for student writing. This is because these sources, written for academic audiences of specific fields, are helpful for developing your argument on many topics of interest in the academic realm, from history to biology.
Summary. A strong presentation is so much more than information pasted onto a series of slides with fancy backgrounds. Whether you're pitching an idea, reporting market research, or sharing ...
Trump, however, has sought to publicly distance himself from the effort, as reported by The Washington Post. "I know nothing about Project 2025," Trump wrote in a July 5 Truth Social post ...
Similarity Report and AI Writing guidance: Academic integrity tools: Creating PeerMark assignments guidance: Class and assignment management: Creating and managing QuickMarks, rubrics and grading PeerMark assignments guidance: Grading and feedback: User profile guidance for administrators and instructors: User profile settings
Complex health interventions (CHIs) are increasingly used in public health, clinical research and education to reduce the burden of disease worldwide. Numerous theories, models and frameworks (TMFs) have been developed to support implementation of CHIs. This systematic review aims to identify and critique theoretical frameworks concerned with three features of implementation; adaptability ...
Plant carbon (C) concentration is a fundamental trait for estimating C storage and nutrient utilization. However, the mechanisms of C concentration variations among different tree tissues and across species remains poorly understood. In this study, we explored the variations and determinants of C concentration of nine tissues from 216 individuals of 32 tree species, with particular attention ...
Three graduate students from McGill University's Department of Integrated Studies in Education (DISE) have been honoured with prestigious fellowships and awards for their international research endeavours. Renee Davy, a PhD candidate in Educational Studies, is a 2023 recipient of the International Doctoral Research Awards (IDRA). Funded by the International Development Research Centre (IDRC ...
COMMENTS
Rolex Yacht-Master II. NEW Yacht-Master II Steel Rose Gold 116681 Bx WARRANTY DATED 2024 #RL9.2. $ 28,395. + $150 for shipping. US. Rolex Yacht-Master II. 116681 Yacht-Master II 44mm Rose Gold White Dial Blue Ceramic Bezel Complete Set 2016. $ 19,900. Free shipping.
Precious on land and at sea. Available in three diameters - 37, 40 and 42 mm - and in various precious versions - 18 ct yellow, white and Everose gold - as well as in Everose Rolesor and Rolesium versions, the Yacht-Master is unique in the world of Rolex professional watches.
THE CASE: If you've been around Rolex circles for any serious amount of time, you'll likely have heard that the Yacht-Master II is simply too large of a watch for Rolex to have made - And to be fair, it's very big by Rolex standards. The watch is the only Rolex produced that measures in at 44mm with a significant 14mm thickness and is made of 904L Stainless Steel.
In 2010, Rolex released one of the most controversial models in the brand's recent history: the Yacht-Master II.The original Yacht-Master from the 1990s is effectively a more luxurious version of the popular Submariner with a slightly toned-down tool watch feel. The Yacht-Master II, however, strikes an entirely different chord.
The 18 kt yellow gold and 18 kt white gold versions are reserved for the Yacht-Master 42. Rolex gold is also combined with Oystersteel - a particularly corrosion-resistant alloy - for the Everose Rolesor versions of the Yacht-Master 37 and Yacht-Master 40. They combine a bezel and centre links in Everose gold with a middle case, winding ...
The first versions of the Rolex Yacht Master II to be unveiled were the 18k yellow gold ref. 116688 and the even more opulent 18k white gold version fitted with a platinum bezel, the ref. 116689. Quite a bit removed from the brand's usually conservative styling, this large, gleaming, in-your-face effort that shouted its own name across its ...
The Rolex Yacht-Master II features one of the brand's most complicated in-house movements to date — the self-winding mechanical chronograph, caliber 4160/4161. This movement boasts high-tech features like a countdown timer with both flyback and fly-forward functionality and a mechanical memory with on-the-fly chronograph synchronization ...
Yacht-Master II Reference 116681 Key Features: Reference Number: 116681 Year of Introduction: 2011 Case Size: 44mm Materials: Everose Rolesor (wo-tone stainless steel and Everose gold) Functions: Time w/ running seconds, regatta chronograph featuring a programmable countdown timer with mechanical memory and on-the-fly synchronization Dial: White w/ Luminous Hour Markers
The Rolex Yacht-Master is a collection of watches built for yachting and sailing. It is composed of two families of watches: the Yacht-Master, a luxury watch designed to be worn on while lounging on a boat; and the Yacht-Master II, a functional sports watch designed to accurately time the start of a regatta race.
The Rolex Yacht-Master II was specifically designed for regatta yacht races where the starting procedure of the race requires each yacht to be positioned as best as possible when a given time limit expires. From what I understand this time limit before the actual start varies between 5 and 10 minutes and so skippers need a regatta timer watch ...
The Rolex Yacht-Master II is a sport watch made by Rolex, unveiled in 2007 and first introduced in March 2010 with the models 116688 (Yellow Gold) and 116689 (White Gold).One year later, in 2011, Rolex introduced the model 116681 which was made from steel and everose gold. [1] At Baselworld 2013, the watch was available for the first time in 904L steel, the model 116680, fitted with a ...
The Rolex Yacht-Master 116688 has a last known retail price of $43,500 and trades for $38,717 on the pre-owned market. Expect to pay 8% more when buying from a secondary market dealer. The Rolex 116688 is a discontinued model, and is not currently in production. See Rolex 116688 for Sale. We've tracked 299 sales for the Rolex 116688 in the past ...
Discover the Yacht-Master 42 watch in RLX titanium on the Official Rolex Website. Model:m226627-0001. ... 3235, Manufacture Rolex. Precision-2/+2 sec/day, after casing. Functions. Centre hour, minute and seconds hands. Instantaneous date with rapid setting. Stop-seconds for precise time setting.
Rolex FINALLY did it!!! They got rid of the Yacht-Master II—at Watches and Wonders 2024—which historically was my least favorite modern Rolex. Although there were some cool characteristics, like being the only other Rolex Chronograph beside the Daytona, I could just never get into the Yacht-Master II. I would go so far as to say the Rolex ...
OYSTER PERPETUAL YACHT-MASTER II. YACHT-MASTER II OYSTER PERPETUAL. 5. 7. 8.
Rolex Yacht-Master II Listing: $35,950 Rolex Yacht-Master II, Reference number 116688; Yellow gold; Automatic; Condition Good; Location: United States of Ame
er Perpetual Yacht-Master II isa unique regatta chronograph dedicated to both yachting enth. siasts and experi-enced sailors. It features a countdown function with a mechanical memory programmable from 1 to 10 minutes and which can be synchronized on the fly - a function that responds to the need for precise timing during the crucial.
Brand: Rolex. Model: Yacht-Master. Model Number: 116680. The Rolex Pro-Hunter Model 116680 is a distinct timepiece, well-suited to the discerning gentleman. Manufactured in 2016, this watch is in excellent condition and comes with a 2-year warranty. It features an automatic movement encased in a 44mm PVD case, complemented by a black baton dial ...
First released at Baselworld 2019, the Yacht-Master 42 is the newest and largest addition to the Rolex Yacht-Master lineup. Historically, the Yacht Master collection has been the only Rolex sports model available in multiple sizes; however, until the release of the Yacht-Master 42 ref. 226659, 40mm was the largest case size available.
Rolex currently offers the Yacht-Master and the Yacht-Master II. The former is available in three sizes - 42, 40, and 37 mm. The Yacht-Master features a bi-directional rotating bezel made of precious materials. The 60-minute graduated bezel with its raised polished numerals and graduations ensures reading in tough conditions.
Yacht-Master. diameter-37; diameter-40; diameter-42; diameter-44; Yacht-Master 42. Oyster, 42 mm, RLX titanium. Yacht-Master 40. Oyster, 40 mm, Everose gold. Rolex ...
The largest selection of authentic luxury watches for sale: Rolex, Omega, Patek Philippe, and more! Find great deals from sellers in your area. Skip. Have you tried the Chrono24 app? Discover now ! ... Rolex Yacht-Master; Patek Philippe Calatrava; Hublot Big Bang; IWC Portuguese; Rolex Explorer II; IWC Pilot; Zenith El Primero; Omega ...
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Discover the experience of buying a Rolex at our store in Petrovka ul. 2 125009 Moscow Russia. Skip to content Skip to footer. Menu. Search. Store locator. Favourites ... GMT-Master II; Oyster Perpetual; Sea-Dweller; Deepsea; Sky-Dweller; Submariner; Yacht-Master; 1908; Watchmaking. At the core of excellence; Behind the seal; Rolex anatomy ...